WebCompound 5a elicited lethal rather than inhibition effects on SK-MEL-5 melanoma cell line, 786-0, A498, RXF 393 renal cancer cell lines, and MDA-MB-468 breast cancer cell line. Two compounds, 5a and 5d showed promising mean growth inhibitions and thus were further tested at five-dose mode to determine median inhibitory concentration (IC50) values. WebCompound Viability screens Drug sensitivity AUC (Sanger GDSC1) Drug sensitivity AUC (Sanger GDSC2) Drug sensitivity IC50 (Sanger GDSC1) Drug sensitivity IC50 (Sanger …
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WebApr 1, 2004 · RXF 393 controls expressed 8.7 pg TNF-α /μg protein, rofecoxib 2.5 and nimesulide treated tissue contained 2 pg/μg TNF-α. Accordingly, PGE2 production was inhibited by both, rofecoxib and nimesulide in cultures of cachectic tumors (IC 50 at 24 hr = 100 μM). Our data indicate that TNF-α is the only discriminative cytokine in cachexia and ... WebJul 21, 2024 · Reconstitution of PGC1α in both CAKI-1 and RXF-393 cells reduced mRNA expression of COLs (Fig. (Fig.2A 2A and fig. S2B). Stable expression of PGC1α resulted in decreased protein levels of COL1A1, COL6A2, and COL11A1 in both CAKI-1 and RXF-393 cells (Fig. 2B). We initially considered if this finding could be mediated by TGF-β signaling, … bca duration in karnataka
RXF.393 Cell Avalanche® Transfection Reagent (human kidney carcinoma …
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